FORENSIC PATHOLOGY AND CHIMERAS
This is one of those "fun" articles that I had to blog about, because it has all sorts of not-so-fun implications. It was spotted by N., who passed it along, and who gets a big thank you for doing so. The reason N. sent it along and the reason I'm blogging about it is the overall context that has been going on in the wonderful world of the modern Dr. Frankensteins working in their laboratories creating chimeras, fusions of mice and pigs and monkies and men. For that matter, we might also include the wonderful world of the modern millionaire Draculas who like to have "young blood" transfusions to maintain their youth. The standard internet theory is that they've got to have that adrenochrome, and hence, it's all the better if that "young blood" comes from a traumatized baby or child... you get the contextual picture. This contextual picture forms part of today's high octane speculation (and I mean, it's really high octane).
The article that N. sent concerns a Nevada gentleman who received a bone marrow transplant, but who then discovered that the DNA of his donor, a German gentleman thousands of miles away, was not only showing up in his own blood, but that it was showing up elsewhere in his body: in his saliva, in his semen, and so on and so forth. He was a true, genuine, chimera, carrying two sets of DNA:
Now, years ago, when all this inter-species miscegenation called "gene splicing" started gaining some real attention, and when GMOs and cross-plant genetic engineering started occurring, I blogged about a wild and crazy idea (and of course, was immediately blasted for it), but I'm going to repeat that high octane speculation once again, though this time, in the context afforded by this story. The wild and woolly speculation was that what if the consumption of chimerical plants over time broke down the body's natural defenses? Suppose, in other words, there was some kind of "epi-genetic barrier" that was a defense mechanism, but that it could degrade over time and with consistent consumption of chimerical (engineered) food? Would aspects of that engineered DNA start showing up in our own? Well, needless to say there were more than a couple of people who piled on me like a quarterback being sacked. Their point was, we don't turn into chickens if we eat omelettes, or into pigs, lettuce, or tomatoes if we eat bacon, lettuce and tomato sandwiches. But that wasn't really my point anyway.
But now in the case of Mr. Long in Nevada, who received a bone marrow transplant from a donor in Germany, it seems that not only is the donor's DNA showing up in Mr. Long's blood (which would be predictable), but that it's showing up in places were it "shouldn't", like Mr. Long's saliva and semen. Well, that too is predictable in a way: semen typically has very small amounts of blood mixed in, and both the mouth and the male sexual organ are served by lots of little capillaries. But there's a problem here too:
But four years after his lifesaving procedure, it was not only Mr. Long’s blood that was affected. Swabs of his lips and cheeks contained his DNA — but also that of his donor. Even more surprising to Mr. Long and other colleagues at the crime lab, all of the DNA in his semen belonged to his donor. “I thought that it was pretty incredible that I can disappear and someone else can appear,” he said.
One now sees why crime labs would have an interest in Mr. Long's chimerical case: if, say, he were to have children, who would be the father? Mr. Long's donor in Germany? Or Mr. Long himself? We already have a precedent in human adoption cases: typically, we ignore biology, and look at who's actually doing the fathering or mothering in cases like this: who has assumed the responsibility of emotional support and so on. That aspect is easy. But the article discloses something intriguing here: it was once thought by the "experts" to be completely impossible:
Three bone marrow transplant experts who were surveyed agreed that it was an intriguing question. They also agreed that passing on someone else’s genes as a result of a transplant like Mr. Long’s was impossible.
“There shouldn’t be any way for someone to father someone else’s child,” said Dr. Rezvani, the Stanford medical director.
That’s not to say that other forms of chimerism haven’t created comparably confusing scenarios. Fraternal twins sometimes acquire each other’s DNA in the womb; in at least one case that led to unfounded fears of infidelity when a man’s child did not seem to be his. In another case, a mother nearly lost custody of her children after a DNA test.
But a donor’s blood cells should not be able to create new sperm cells, Dr. Rezvani said. Dr. Mehrdad Abedi, the doctor at the University of California, Davis, who treated Mr. Long, agreed: He believed it was Mr. Long’s vasectomy that explained how his semen came to contain his donor’s DNA. The forensic scientists involved say they plan to investigate further. (Emphasis added)
In other words:
EXPERT: It shouldn't and can't happen.
REALITY: But it did.
So, what if Mr. Long's semen production of his donor is not due to Mr. Long's vasectomy, but rather to something else?
It's that "something else" I want to explore as my high octane speculation. What if we've created, through widespread use of genetic engineering and fusions - what I'm calling "inter-species miscegenation" - a breakdown of some sort of "epigenetic barrier" that will only increase over time? It's an intriguing idea to ponder, if for no other reason than that it seems so counter-intuitive and against the grain of the paradigms of speciation we've been taught and that have been hammered into us in school. If that wild and woolly high octane speculation is true, then possibly one way it might begin to manifest itself is that the breakdowns will start to occur on a case-to-case basis, in individuals whose natural "epigenetic barrier defenses against chimerism have for whatever reason, such as health issues, been weakened. Over time, it grows to the extent that chimerical species take over from current ones as the next leap of "evolution", or over time, species grow increasingly together and not apart (and yes, that obviously has all sorts of nasty implications for various forms of Darwinism).
So my prediction, if my little experimental hypothesis is true, is that over time we'll see more and more stories like this one. But in the meantime, because it is such a nutty idea, you can all pile on!
See you on the flip side...
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Anyone remember the stories repeated about the Dulce DUMB??? We’ve already “been there…done that”….it’s just that The Public was never “in the know” about it all.
How about reading Atrahasis??? My opinion is that we have been locked into a certain “mindset” for over 2,000 years & thought we had to interpret everything according to the mindset imposed upon us. Would that be part of the reason that much of the “progress” achieved had to kept secret??? We couldn’t even admit that we were not alone in the Universe!!! Our explanation for everything had to fit within a construction that was made by human beings….IF one wanted to “get along”!! 😉
Runic regeneration of morphogenetic field genome:
Parasites seek to breed with the host, to create a blurred outline between categories, so they can infest the host’s body, and take over body politic, to become head of state, by means of prostitution and poison.
To maintain the illusion, the parasites must get rid of all means, that could expose them as alien pretenders. The suppression of the ancient Runes is because the Runes are such a means.
A rightful king was to be versed in Runic metaphors. That was the ancient Druidic rule. The parasites cannot stand the Runes, because the parasites are unable to unriddle the epigenetic Runic “genome”.
The parasites cannot define the host by Runes, without entering into paralysis – an epistemological paradox – and that is the whole point, when ensnaring dragons in a loop.
A caught dragon bites its own tail.
From cited article: “…received a bone marrow transplant, but who then discovered that the DNA of his donor, a German gentleman thousands of miles away, was not only showing up in his own blood, but that it was showing up elsewhere in his body…”
I remember reading somewhere that bone marrow cells still contained either some embryonic stem cells or at least stem cells that were only one stage removed from them and could produce body cells of different types – indefinitely. Immortal cells…
From cited article: “…diagnosis of acute myeloid leukemia and myelodysplastic syndromes…”
I also seem to remember that one ‘cure’ for these cancers was a really-heavy dose of radiation (plus chemotherapy) that killed-off the cancer cells but also killed-off the embryonic stem cells (or at least varied types of stem cells) in the bone marrow. Hence, a bone marrow transplant to keep the body from ‘running down’ with the lack of replacement cells for those ageing-out with time.
If the above is true, the only ‘new’ cells being produced in his body would be derived from the transplant cells (not his original DNA). The ‘surprise’ here is that the body has ways to distribute those ‘new’ cells throughout the body, to wherever needed. I seem to remember Dr. Robert O. Becker’s body electromagnetic fields were implicated in that regard…
(In the long run, if the man lived to an extended lifespan, all his original DNA cells would age-out and be replaced by the substituted DNA. This would provide an interesting ‘experiment’ as to how much of our consciousness is DNA-derived or neuron-networking derived versus originating from ‘outside’.)
High octane speculation side:
Rather than a biologically-based “breakdown of some sort of ‘epigenetic barrier’ that will only increase over time,” what if it was Dr. Rupert Sheldrake and his morphogenetic fields at work? First time, “epigenetic barrier defenses against chimerism” would be strong, due to morphogenetic field ‘habit’. Over time, repetition would weaken this barrier. A new morphogenetic field would arise. This effect could be accidental, or could be quite deliberate…
um. yeh Doc. I’ll pile on. Perhaps not the way to expected.
The Truth About Stem Cells
Does bone marrow share some significant part in stem cells which in turn share some significant part in well every cell?
Good point ragiza. I thought I thought of it first – till I read the rest of the comments.
I know of a novel written by a French author I think the title was Prime Cuts dealt with the idea. It was published in the mid-sixties of the last century I did not read the novel the donor was an executed criminal and the novel dealt with the effects of patients receiving body parts form this criminal.
Look no further than China the last couple decades, right?
Genetically engineered viruses can alter DNA of healthy cells by inserting new ones. Be interesting if this can be used to eliminate transplant rejection once its mechanism becomes known. I have noticed that couples who have been together for a long time often start looking like they are related. Perhaps DNA swapping is more prevalent than we realize. Whats dangerous is designer proteins that don’t exist in nature but can replace those that are natural and cause either better or worse function.
Spot on Roger!
Great speculations…thanks for sharing them!
Good one. That was the second think I thought of.
Mankind may have an ancient Frankenstein ancestor who also practiced in laboratories creating chimeras. In fact, to see his experiment, just look into the mirror. This mirror fascination has recently been weaponized as a social mirror[the device everybody is glued to].
Yes, those newly exposed rich Draculas’ employing their needles into just-in-time bloody fountains of youth; mirroring their more advanced mosquito cousins, that actually use six sophisticated needles.
Of course, Dracula is more inhumanly sophisticated, in that their rich species prefers baby sacrifices.
Now that’s exactly where I was going as I read along…
evolution, but not the trumped up Darwin myth; but your metaphor theory that delves into the “non-locality’ realms of change. One I ascribe to.
Your post connects.
Don’t play w/genetic fire; or,
you get an unwanted, questionable? mirrored? reflection?
Interesting and provocative.
Bone marrow is the source of stem cells and maybe transplants of bone marrow are particularly vulnerable to leading to any actual “chimering” effects.
One also wonders whether living donors of live tissue suffer what could be termed “post procedure bouts of bilocations.”
Or post partum depression?
A thought experiment.
What happens if the German dies before Mr. Long ?
Will that soul be attracted to and cohabit Mr. Long’s body ?
If Mr. Long does NOT currently speak German, will he suddenly become fluent in German ?
In case of a “cohabitation”, will Mr. Long be diagnosed with schizophrenia ?
What if the German donor’s personality evicts Mr. Long’s identity from “his” body
Would Mr. Long’s body have then been snatched ?
It’d be interesting to find out if they did a DNA on Mr. Long’s spermatozoa, not just his seaman.
On a side note, would anyone be aware of any study that analyzed and compared the DNA make up of every spermatozoon in an ejaculate for uniformity ?
What about a similar study on the spermatozoa from ejaculates over life span ?
Have all biological assumptions been subjected to rigorous verification ?
Inquiring minds would like to know ….
funny how all those long term biological assumptions never get questioned let alone assessed in an epigenetic light.
BTW, it might be nice to review some of the history behind the Galton/Darwin perspectives that brought us those consensus science points called Darwinism. Nooooo, I would not dare argue with evolution THEORY. That would make me some kinda nutter right? What does seem so obvious as to be consistently overlooked is how badly even the most acceptable parts of Darwinism are understood and applied.